Research plan

1. Mechanism of mRNA Subcellular Localization

1.1 Development of new methods for single-molecule imaging of endogenous mRNA in live cells.

1.2 Dynamics of mRNA targeting

1.3 mechanism of mRNA targeting

2. Function of Organelle-Associated Membrane-less Organelles in Biology and Disease

2.1 Identification of endoplasmic reticulum and mitochondrial associated membrane-less organelles

2.2 Development of new tools to identify the composition of membrane-less organelles.

2.3 RNA granules and neurodegenerative diseases

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