#Co-first  *Co-corresponding

1.     Huang D*, Tran JT, Peng L, Yang L, Suhandynata RT, Hoffman MA, Zhao F, Song G, He W-t, Limbo O, Callaghan S, Landais E, Andrabi R, Sok D, Jardine JG, Burton DR, Voss JE, Fitzgerald RL, Nemazee D*. A Rapid Assay for SARS-CoV-2 Neutralizing Antibodies That Is Insensitive to Antiretroviral Drugs. The Journal of Immunology. 2021:ji2100155.

2.     Yuan M^#, Huang D^#, Lee C-CD^#, Wu NC^#, Jackson AM, Zhu X, Liu H, Peng L, van Gils MJ, Sanders RW, Burton DR, Reincke SM, Prüss H, Kreye J, Nemazee D, Ward AB, Wilson IA. Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Science. 2021:eabh1139. doi: 10.1126/science.abh1139.

3.     Wu NC^#, Yuan M^#, Bangaru S^#, Huang D^#, Zhu X, Lee C-CD, Turner HL, Peng L, Yang L, Burton DR, Nemazee D, Ward AB, Wilson IA. A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. PLOS Pathogens. 2020;16(12):e1009089. doi: 10.1371/journal.ppat.1009089.

4.     Rogers TF^#, Zhao F^#, Huang D^#, Beutler N^#, Burns A, He W-t, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science. 2020:eabc7520. doi: 10.1126/science.abc7520.

5.     Huang D, Tran JT, Olson A, Vollbrecht T, Tenuta M, Guryleva MV, Fuller RP, Schiffner T, Abadejos JR, Couvrette L, Blane TR, Saye K, Li W, Landais E, Gonzalez-Martin A, Schief W, Murrell B, Burton DR, Nemazee D, Voss JE. Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nature communications. 2020;11(1):5850. doi: 10.1038/s41467-020-19650-8.

6.     Huang D^#, Abbott RK^#, Havenar-Daughton C, Skog PD, Al-Kolla R, Groschel B, Blane TR, Menis S, Tran JT, Thinnes TC, Volpi SA, Liguori A, Schiffner T, Villegas SM, Kalyuzhniy O, Pintea M, Voss JE, Phelps N, Tingle R, Rodriguez AR, Martin G, Kupryianov S, deCamp A, Schief WR, Nemazee D, Crotty S. B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models. Proceedings of the National Academy of Sciences. 2020:202004489. doi: 10.1073/pnas.2004489117

7.     Gavin AL^#, Huang D^#, Huber C^#, Martensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D. PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing. Nature immunology. 2018;19(9):942-53. Epub 2018/08/17. doi: 10.1038/s41590-018-0179-y. PubMed PMID: 30111894; PMCID: PMC6105523.

8.     Huang D^#, Zheng X^#, Wang ZA^#, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J. The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process. Molecular and cellular biology. 2017;37(5). Epub 2016/12/07. doi: 10.1128/mcb.00497-16. PubMed PMID: 27920255; PMCID: PMC5311246.

Other publications

1.     Zhou X, Ma F, Xie J, Yuan M, Li Y, Shaabani N, Zhao F, Huang D, Wu NC, Lee C-CD, Liu H, Li J, Chen Z, Hong Y, Liu W-H, Xiao N, Burton DR, Tu H, Li H, Chen X, Teijaro JR, Wilson IA, Xiao C, Huang Z. Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2. Cell reports. 2021;35(6):109109.

2.     Song G, He W-t, Callaghan S, Anzanello F, Huang D, Ricketts J, Torres JL, Beutler N, Peng L, Vargas S, Cassell J, Parren M, Yang L, Ignacio C, Smith DM, Voss JE, Nemazee D, Ward AB, Rogers T, Burton DR, Andrabi R. Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection. Nature communications. 2021;12(1):2938. doi: 10.1038/s41467-021-23074-3.

3.     Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O’Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, Yang L, Hou Y, Scobey TD, Burton DR, Nemazee D, Dye JM, Voss JE, Gunn BM, McLellan JS, Baric RS, Gralinski LE, Walker LM. Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody. Science. 2021;371(6531):823-9. doi: 10.1126/science.abf4830.

4.     Liu H, Yuan M, Huang D, Bangaru S, Zhao F, Lee C-CD, Peng L, Barman S, Zhu X, Nemazee D, Burton DR, van Gils MJ, Sanders RW, Kornau H-C, Reincke SM, Prüss H, Kreye J, Wu NC, Ward AB, Wilson IA. A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host & Microbe. 2021;29(5):806-18.e6. doi: https://doi.org/10.1016/j.chom.2021.04.005.

5.     Yuan M, Liu H, Wu NC, Lee C-CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, Wilson IA. Structural basis of a shared antibody response to SARS-CoV-2. Science. 2020;369(6507):1119-23. doi: 10.1126/science.abd2321.

6.     Wec AZ, Wrapp D, Herbert AS, Maurer DP, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh C-L, Wang N, Nett JH, Champney E, Burnina I, Brown M, Lin S, Sinclair M, Johnson C, Pudi S, Bortz R, Wirchnianski AS, Laudermilch E, Florez C, Fels JM, O’Brien CM, Graham BS, Nemazee D, Burton DR, Baric RS, Voss JE, Chandran K, Dye JM, McLellan JS, Walker LM. Broad neutralization of SARS-related viruses by human monoclonal antibodies. Science. 2020:eabc7424. doi: 10.1126/science.abc7424.

7.     Suhandynata RT, Hoffman MA, Huang D, Tran JT, Kelner MJ, Reed SL, McLawhon RW, Voss JE, Nemazee D, Fitzgerald RL. Commercial Serology Assays Predict Neutralization Activity against SARS-CoV-2. Clinical Chemistry. 2020;67(2):404-14. doi: 10.1093/clinchem/hvaa262.

8.     Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian J-H, Portnoff AD, Patel N, Massare MJ, Yates JR, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB. Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate. Science. 2020:eabe1502. doi: 10.1126/science.abe1502.

9.     Antanasijevic A, Ueda G, Brouwer PJM, Copps J, Huang D, Allen JD, Cottrell CA, Yasmeen A, Sewall LM, Bontjer I, Ketas TJ, Turner HL, Berndsen ZT, Montefiori DC, Klasse PJ, Crispin M, Nemazee D, Moore JP, Sanders RW, King NP, Baker D, Ward AB. Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens. PLOS Pathogens. 2020;16(8):e1008665. doi: 10.1371/journal.ppat.1008665.

10.   Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, Feeney AJ, Nemazee D, Cannon P, Burton DR. Reprogramming the antigen specificity of B cells using genome-editing technologies. eLife. 2019;8. Epub 2019/01/17. doi: 10.7554/eLife.42995. PubMed PMID: 30648968; PMCID: PMC6355199.

11.   He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, Burton DR, Wilson IA, Zhu J. HIV-1 vaccine design through minimizing envelope metastability. Science advances. 2018;4(11):eaau6769. Epub 2018/11/27. doi: 10.1126/sciadv.aau6769. PubMed PMID: 30474059; PMCID: PMC6248932.

12.   Zhang Y, Su SS, Zhao S, Yang Z, Zhong CQ, Chen X, Cai Q, Yang ZH, Huang D, Wu R, Han J. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome. Nature communications. 2017;8:14329. Epub 2017/02/09. doi: 10.1038/ncomms14329. PubMed PMID: 28176780; PMCID: PMC5309790.

13.   Wu T, Li Y, Huang D, Han F, Zhang YY, Zhang DW, Han J. Regulator of G-protein signaling 19 (RGS19) and its partner Galpha-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD-induced autophagy and cell death in L929 cells. PloS one. 2014;9(4):e94634. Epub 2014/04/23. doi: 10.1371/journal.pone.0094634. PubMed PMID: 24751948; PMCID: PMC3994006.

14.   Lin J, Li H, Yang M, Ren J, Huang Z, Han F, Huang J, Ma J, Zhang D, Zhang Z, Wu J, Huang D, Qiao M, Jin G, Wu Q, Huang Y, Du J, Han J. A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell reports. 2013;3(1):200-10. Epub 2013/01/22. doi: 10.1016/j.celrep.2012.12.012. PubMed PMID: 23333278.

15.   Chen X, Li W, Ren J, Huang D, He W-t, Song Y, Yang C, Li W, Zheng X, Chen P, Han J. Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death. Cell Research. 2013;24:105. doi: 10.1038/cr.2013.171.

16.  Chen W, Zhou Z, Li L, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J. Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. The Journal of biological chemistry. 2013;288(23):16247-61. Epub 2013/04/25. doi: 10.1074/jbc.M112.435545. PubMed PMID: 23612963; PMCID: PMC3675564.