H index=55, Google citations>23,000; SCI citations>16,000; 近5年他引近9,000次

 In ZJU：

·      Zou J, Qin Z, Li R*, Yan X, Huang H, Yang B, Zhou F*, Zhang L*. iProPhos: a web-based interactive plastform for integrated proteome and phosphoproteome analysis. Molecular & Cellular Proteomics. 2024
·      Ren J, Wang S, Zong Z, Pan T, Liu S, Mao W, Huang H, Yan X, Yang B, He X, Zhou F*, Zhang L*. TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence. Nature Commaunications. 2024
·      Yuan X, Yan L, Chen Q, Zhu S, Zhou X, Zeng L, Liu M, He X, Huang J, Lu W, Zhang L*, Yan H*, Wang F*. Molecular mechanism and functional significance of Wapl interaction with the Cohesin complex. Proceedings of the National Academy of Sciences (PNAS). 2024
·      Wan S, Zhou X, Xie F*, Zhou F*, Zhang L*. Ketogenic diet and cancer: multidimensional exploration and research. Science China Life Sciences. 2024
·      Bai L, Zhou F*, Zhang L*. Booster vaccination: host preparation against omicron challenge by innate immunity training. MedComm. 2024
·      Guo H, Zhou F*, Zhang L*. Nε-Acetyl-Nε-methyllysine: a new post-translational modification to mark chromatin. MedComm-Future Medicine. 2024
·      Bai L, Zhou F*, Zhang L*. Serotonin signaling: a new player and therapeutic target beyond long-haul coronavirus disease. MedComm. 2024
·      Wei X, Zhou F*, Zhang L*. PARP1-DNA co-condensation: the driver of broken DNA repair. Signal Transduction and Targeted Therapy. 2024
·      Zou J, Qin Z, Zhang L*. High-resolution spatiotemporal mapping: a comprehensive view of eukaryotic cell cycle proteome dynamics. Signal Transduction and Targeted Therapy. 2024
·      Gu Y, Zhou X, Zhang L*. Advances in the elucidation of CircRNA translocation. MedComm-Future Medicine. 2024
·      Shang Y, Shu X, Lu Y, Zhu W, Li R, Fu H, Li C, Sun W, Li Z, Zhang Y, Cao X, Ye X, Emmanuel A, Zhao B, Zhang L, Wu H, Feng XH, Yang B, Lu H. A chaperon-like function of FUS ensures TAZ condensate dynamics and transcriptional activation. Nature Cell Biology. 2024
·      Ding W, Liu C, Chen Y, Gu J, Fang C, Hu L, Zhang L, Yuan Y, Feng XH, Lin S. Computational design and genetic incorporation of lipidation mimics in living cells. Nature Chemical Biology. 2024
·      Yan L, Yuan X, Liu M, Chen Q, Zhang M, Xu J, Zeng LH, Zhang L, Huang J, Lu W, He X, Yan H, Wang F. A non-canonical role of the inner kinetochore in regulating siter-chromatid cohesion at centromeres. EMBO Journal. 2024
·      Liu D, Ding W, Cheng J, Wei Q, Lin Y, Zhu T, Tian J, Sun K, Zhang L, Lu P, Yang F, Liu C, Tang S, Yang B. Characterize direct protein interactions with enrichable, cleavable and latent bioreactive unnatural amino acids. Nature Communications. 2024
·      Li C, Xu X, Geng Z, Zheng L, Song Q, Shen X, Wu J, Zhao J, Li H, He M, Tai X, Zhang L, Mao J, Dong Y, Ren A. Structure-based characterization and compound identification of the wild-type THF class-II riboswitch. Nucleic Acids Research. 2024
·      Tan L, Yan M, Su Z, Wang H, Li H, Zhao X, Liu S, Zhong L, Sun Q, Lu D. R-spondin-1 induces Axin degradation via the LRP6-CK1e axis. Cell Communication and Signaling. 2024
·      Dong X, Lin Y, Li K, Liang G, Huang X, Pan J, Wang L, Zhang D, Liu T, Wang T, Yan X, Zhang L, Li X, Qu X, Jia D, Li Y, Zhang H. Consensus statement on extracellular vesicles in liquid biopsy for advancing laboratory medicine. Clinical Chemistry and Laboratory Medicine. 2024

·      Dai T, Zhang L, Ran Y, Zhang M, Yang B, Lu H, Liu J, Lin S*, Zhang L*, Zhou F*. DeSUMOylation by SENP1 inhibits MAVS aggregation and antagonizes IRF3 activation. Nature Structural & Molecular Biology. 2023
·      Liu S, Ren J, Zhang L*. RHOJ: a key regulator of EMT-associated resistance to chemotherapy. Signal Transduction and Targeted Therapy. 2023
·      Pan C, Zhou F*, Zhang L*. The loss of epigenetic information: not only consequences but a cause of mammalian aging. Signal Transduction and Targeted Therapy. 2023
·      Li R, Zou J, Pei D, Pan T, Yang B, Liu X, Chen Y*, Zhou F*, Zhang L*. Deciphering dynamic changes of the aging transcriptome with COVID-19 progression and convalescence in the human blood. Signal Transduction and Targeted Therapy. 2023
·      Z Zong, Zhou F*, Zhang L*. The fungal mycobiome: a new hallmark of cancer revealed by pan-cancer analyses. Signal Transduction and Targeted Therapy. 2023
·      Su P, Zhou F*, Zhang L*. Motile cilia and microvillar: accomplices of SARS-CoV-2 in penetrating mucus barrier and infecting airway epithelium. Signal Transduction and Targeted Therapy. 2023
·       Gao Z, Wang B, Zhang L*. Activated STING: an icon channel to trigger non-interferon-related functions. Signal Transduction and Targeted Therapy. 2023
·      Yang Q, Wang B, Zheng Q, Li H, Meng X*, Zhou F*, Zhang L*. A review of gut microbiota-derived metabolites in tumor progression and cancer therapy. Advanced Science. 2023
·      Su P, Wu Y, Xie F, Zeng Q, Chen L, Liu Z, Meng X*, Zhou F*, Zhang L*. A review of extracellular vesicles in COVID-19 diagnosis, treatment and prevention. Advanced Science. 2023
·      Ren J, Yu P, Liu S, Li R, Niu X, Chen Y, Zhang Z*, Zhou F*, Zhang L*. Deubiquitylating enzymes in cancer and immunity. Advanced Science. 2023
·      Lan T, Zhou F*, Zhang L*. WNK1, a molecular crowding sensor, links phase separation to cellular physiological stress.  MedComm. 2023
·      Kuang Y, Sun W, Zhang L*. The presence of Y chromosome leads to the difference of cancer in patients with different sexes.  MedComm. 2023
·      Yang Q, Zhang L*, Chen J*. Lactate, a critical regulator of cell proliferation via anaphase promoting complex remodeling. MedComm-Oncology. 2023
·      Tu Y, Zhou F*, Zhang L*. SIK3-HDAC4 signaling pathway: the swith for transition between sleep and wakefulness.  Molecular Biomedicine. 2023
·      Yao Y, Zong Z, Zhang L*. Unlocking γδ T cell power: pathways that boost cancer defense. Molecular Biomedicine. 2023
·      Niu X, Zhou F*, Zhang L*. Microglia regulate the health of central nervous system through myelin. Molecular Biomedicine. 2023
·      Pan C, Xiao Z, Wu C, Zhang L*, Jia J*, Zhen M*. A new method to synthesize multiple gRNA libraries and functional mapping of mammalian H3K4me3 regions. Nucleic Acids Research. 2023
·      Guan J, Zhang L*, Zhou F*. TBK1: a new target for overcoming cancer immunotherapy resistance. Science China Life Sciences. 2023
·      Wu T, Li S, Ran Y, Lin Y, Liu L, Zhang X, Zhou L, Zhang L, Wu D, Yang B, Tang S. Mapping protein direct interactome of oxidoreductases with small molecular chemical cross-linkers in live cells. Redox Biology. 2023
·      Liao Q, Shu X, Sun W, Mandapaka H, Xie F, Zhang Z, Dai T, Wang S, Zhao J, Jiang H, Zhang L, Lin J, Li S, Coin I, Yang F, Peng J, Li K, Wu H, Zhou F, Yang B. Capturing Protein-Protein interactions with acidic amino acids reative cross-linkers. Small. 2023
·      Shu X, Liao QQ, Li ST, Liu L, Zhang X, Zhou L, Zhang L, Coin I, Wang L, Wu H, Yang B. Detecting active deconjugating enzymes with genetically encoded activity-based ubiquitin and ubiquitin-like protein probes. Analytical Chemistry. 2023   
·      Niu X, Zhang L, Wu Y, Zong Z, Wang B, Liu J*, Zhang L*, Zhou F*. Biomolecular condensates: formation mechanisms, biological functions and therapeutic targets. MedComm. 2023
·      Qin Z, Fang X, et al., Zhou F*, Zhang L*. Deacetylation by SIRT1 enables liquid-liquid phase separation of IRF3/IRF7 in innate antiviral immunity. Nature Immunology. 2022
·      Zhou F*, Zhang L*. IRF3 and IRF7 require SIRT1 for LLPS and transactivation of IFN-I. Nature Immunology. 2022
·      Xie F, Zhou X, Li H, Su P, Liu S, Li R, Zou J, Wei X, Pan C, Zhang Z, Zheng M, Liu Z, Meng X, Ovaa H, Ten Dijke P*, Zhou F*, Zhang L*. USP8 promotes cancer progression and extracellular-vesicle mediated CD8+ T cell exhaustion by deubiquitinating TGF-β receptor TβRII. EMBO Journal. 2022
·      Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, Van Dam H, Ten dijke P, Zhang L*, Zhou F*. Breast Cancer Cell-derived Extracellular Vesicles Promote CD8+ T cell Exhaustion via TGF-β type II receptor Signalling. Nature Communications. 2022
·      Wang S, Chu F, Xia R, Guan J, Zhou L, Fang X, Dai T, Xie F, Zhang L* and Zhou F*. LPA Maintains Innate Antiviral Immunity in a pro-active state via STK38L-Mediated IRF3 Ser303 Phosphorylation. Cell Reports. 2022
·      Fang X, Zhang L*. ZBP1 contributes to interferonopathies caused by impaired ADAR1 function. Molecular Biomedicine. 2022
·      Guan J，Zhang L*, Zhou F*. PI3K-PANK4: a new target for de novo synthesis of coenzyme A. Molecular Biomedicine. 2022
·       Wang B, Zhang L, Zhou F*. Zhang L*. Potential mechanisms by which impaired ketogenesis links metabolism to T-cell dysfunction in patients with severe COVID-19. Medcomm. 2022
·       Wei X, Xie F, Zhou X, Yan H, Liu T, Huang J*, Wang F*, Zhou F*, Zhang L*. Developments in the understanding of pyroptosis and its potential role in the treatment of inflammation and cancer. Cellular & Molecular Immunology. 2022
·       Su P, Zhang L, Zhou F*, Zhang L*. Circular RNA vaccine, a novel mRNA vaccine design strategy for SARS-COV-2 and variants. MedComm. 2022
·       Li J, Zhang M, Ma W, Yang B, Lu H, Zhou F*, Zhang L*. Post-translational modifications in liquid-liquid phase separation：A comprehensive review. Molecular Biomedicine. 2022
·      Zhao L, Zhou X, Xie F, Zhang L, Yan H, Huang J, Zhang C*, Zhou F*, Chen J*,  Zhang L*. Ferroptosis in cancer and cancer immunotherapy. Cancer Communications. 2022
·      Wang Y, Zhou F*, Zhang L*. Cuprotosis: A new form of programmed cell death. Cellular & Molecular Immunology. 2022
·      Li H, Zhou F*, Zhang L*. STING, a critical contributor to SARS-CoV-2 immunopathology.  Signal Transduction and Targeted Therapy. 2022
·      Qin Z, Zhou F*, Zhang L*. Novel pyroptosis-independent functions of gasdermins.  Signal Transduction and Targeted Therapy. 2022
·      Wang B, Zhang L, Wang Y, Dai T, Qin Z, Zhou F, Zhang L*. Alteration in microbiota of Patients with COVID-19: Potential mechanisms and therapeutic interventions.  Signal Transduction and Targeted Therapy. 2022
·       Ren J，Zhang Z, Zong Z, Zhang L*, Zhou F*. Emerging implications of phase separation in cancer. Advanced Science. 2022
·       Pei D, Zhang L*, Zhang Z*. Tumor–neuron interactions: a novel concept contributor to glioblastoma invasion.  MedComm-Oncology. 2022
·       Wang Y，Fang X, Wang S, Wang B, Chu F, Zhang L*, Zhou F*. The role of O-GlcNAcylation in innate immunity and inflammation. Journal of Molecular Cell Biology. 2022 
·       Xie Y，Xie F, Zhou X，Zhang L, Yang B, Huang J, Wang F, Yan H, Zeng L*, Zhang L*, Zhou F*. Microbiota in tumors: from understanding to application. Advanced Science. 2022
·       Tu Y, Fang P, Zhang L*, Sun K*. Analysis of the effect of Snai family in breast cancer and immune cell. Front. Cell Dev. Biol. 2022
·      Fan Y, Xiang Li, Zhang L, Wan S*, Zhang L*, Zhou F*. SARS-CoV-2 Omicron variant: rencent progress and future perspectives. Signal Transduction and Targeted Therapy. 2022
·      Fan Y, Li X, Zhang L, Zhang L*, Zhou F*. SUMOylation in viral replication and  antiviral defense.  Advanced Science. 2022
·      Editorial: TGF-β and BMP signaling in cancer. Yan X, Zhang L, Miyazawa K, Ten Dijke P.  Front. Cell Dev. Biol. 2022
·       Zheng L, Liu J, Niu L, Mohammad K, Yang A, Arttu J, Dai Q, Timothy R, Dinshaw J, Zhang L, Supriya G, Yang Y, Ren A, Eric C. Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins. Genes & development. 2022
·      Yao T, Wang S, Zhang L, Johnson L, Zhou F*. Opsonizing antibodies mediated SARS-CoV-2 entry into monocytes leads to inflammation. MedComm-Future Medicine. 2022
·     Huang Y, Liu S, Shan M et al., Zhang L, Li D, Ten Dijke P. RNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis. Cell Death Disease. 2022
·      Lyengar PV, Marvin DL, Lama D, Tan TZ, Suriyamurthy S, Xie F, van Dinther M, Mei H, Verma CS, Zhang L, Ritsma L, Ten Dijke P. TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signaling. Molecular Cancer Research. 2022
·     Xie F, Su P, Pan T, Zhou X, Li H, Huang H, Wang A, Wang F, Huang J, Yan H, Zeng LH, Zhang L*, Zhou F*. Engineering extracellular vesicles enriched with palmitoylated ACE2 as COVID-19 therapy. Advanced Materials. 2021
·      Li H, Zhou F*, Zhang L*. ADP-riboxanation-A new pyroptosis evasion strategy. Journal of Molecular Cell Biology. 2021
·      Dong Y, Dai T, Wang B, Zhang L, Zeng L, Huang J, Yan H, Zhang L*, Zhou F*. The way of SARS-CoV-2 vaccine development: sucess and challenges. Signal Transduction and Targeted Therapy. 2021
·     Fan Y, Zhang L*, Zhou F*. cGAS-like receptors: new RNA sensors in Drosophila. Signal Transduction and Targeted Therapy. 2021
·      Jin K, Zhou F, Zhang L*. Cancer Environment Immunotherapy: targeting TGF-β finds its way towards tissue healing and vasculature remodeling. Signal Transduction and Targeted Therapy. 2021
·      Xie Y, Xie F, Zhang L, Zhou X, Huang J, Wang F, Jin J, Zhang L*, Zeng L*, Zhou F*. Targeted anti-tumor immunotherapy using tumor infiltrating cells. Advanced Science. 2021 
·      Cao J, Zhang M, Wang B, Zhang L*, Zhou F*, Fang M*. Chemoresistance and metastasis in breast cancer molecular mechanisms and novel clinical strategies. Frontiers in Oncology. 2021   
·      Wang S, Dai T, Qin Z, Pan T, Chu F, Lou L, Zhang L, Yang B, Huang H, Lu H, Zhou F. Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity via elevating MAVS activity. Nature Cell Biology. 2021
·       Wang B, Zhang L, Dai T, Qin Z, Lu H, Zhang L*, Zhou F*. Liquid-liquid phase separation in human health and diseases. Signal Transduction and Targeted Therapy. 2021 
·       Zong Z, Wei Y, Ren J, Zhang L, Zhou F. The intersection of COVID19 and cancer: signaling pathways and treatment implications. Molecular Cancer. 2021
·      Zheng Q, Zhang M, Zhou F, Zhang L, Meng X. The Breast Cancer Stem Cells Traits and Drug Resistance. Frontiers in Pharmacology. 2021
·      Wang B, Dai T, Ren J, Zhang L, Zhou F. Protein N-myristoylation: functions and mechanisms in control of innate immunity. Cellular & Molecular Immunology. 2021 
·      Liu J, Yuan B, Cao J, Luo H, Gu S, Zhang M, Ding R, Zhang L, Zhou F, Hung MC, Xu P, Lin X, Jin J, Feng XH. AMBRA1 promotes TGF-β signaling via non-proteolytic polyubiquitylation of SMAD4. Cancer Research. 2021
·      Gao C, Deng J, Zhang H, Li X, Gu S, Zheng M, Tang M, Zhu Y, Jin J, Zhang L, Huang J, Zou J, Xia Z, Xu P, Shen L, Zhao B, Feng XH. HSPA13 facilitates NF-kB-mediated transcription and attenuates cell death responses in TNFa signaling. Science Adavances. 2021
·      Lin T, Wang S, et al., Zhang L, et al., Ding H, Weng HL. Follistatin-controlled activin-HNF4a-coagulation factor axis in liver progenitor cells determines outcome of acute liver failure. Hepatology. 2021
·      Liu C, Wu T, Shu X, Li S, Wang D, Wang N, Zhou R, Yang H, Jiang H, Hendriks I, Gong P, Zhang L, Nielsen M, Liu K, Wang L, Yang B. Identification of protein direct interactome with genetic code expansion and search engine openuaa. Advanced Biology. 2021
·      Chen Q, Zhang M, Pan X, Yuan X, Zhou L, Yan L, Zeng L, Xu J, Yang B, Zhang L, Huang J, Lu W, Fukagawa T, Wang F, Yan H. Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure acurate chromosome segregation. Cell Reports. 2021
·      Zhu Y, Yu J, Gu J, Xue C, Zhang L, Chen J, Shen L. Relaxed 3D genome conformation facilitates the pluripotent to totipotent-like transition in embryonic stem cells. Nucleic Acids Research. 2021
·      Liu S, Gonzalez-Prieto R, Zhang M, Geurink PP, Kooij R, Lyengar PV, van Dinther M, Bos E, Zhang X, Le Devedec SE, van de Water B, Koning RI, Zhu HJ, Mesker WE, Vertegaal ACO, Ovaa H, Zhang L, Martens JWM, Ten Dijke P. Deubiquitinase activity profiling identifies UCHL1 as a candidate oncoprotein that promotes TGF-β-induced breast cancer metastasis. Clinical Cancer Research. 2020
·     Zhang Z, Fang X, Wu X, Chu F, Ling L, Li J, Wang S, Zang J, Zhang B, Ye S, Zhang L, Yang B, Lin S, Huang H, Wang A, Zhou F.  Acetylation-dependent deubiquitinase OTUD3 controls MAVS activation in innate antiviral immunity. Molecular Cell. 2020
·     Li T, Wu B, Yang T, Zhang L, Jin K. The outstanding antitumor capacity of CD4+ T helper lymphocytes. BBA-Reviews on Cancer. 2020
·      Cao J, Zhang M, Xie F, Lou J, Zhou X, Zhang L, Fang M, Zhou F. Exosomes in Head and Neck Cancer: Roles, Mechanisms and Applications. Cancer Letters. 2020
·      Cao J, Zhang M, Zhang L, Lou J, Zhou F, Fang M. Non-coding RNA in thyroid cancer-Functions and mechanisms. Cancer Letters. 2020
·     Zong Z, Zhang Z, Wu L, Zhang L, Zhou F. The functional deubiquitinating enzymes in control of innate antiviral immunity. Advanced Science. 2020
·     Dong Y, Dai T, Wei Y, Zhang L, Zheng M, Zhou F. A systematic review of SARS-CoV-2 vaccine candidates. Signal Transduction and Targeted Therapy. 2020 
·     Dong Y, Dai T, Zhang L, Zhou F. Coronavirus in continuous flux: from SARS-CoV to SARS-CoV-2.  Advanced Science. 2020
·      Jin K, Zhang L, Zhou F. An Effective Platform for Cancer Immunotherapy: Pooled Knockin Targeting for Genome Engineering Immunotherapies. Signal Transduction and Targeted Therapy. 2020 
·      Cheng Z, Dai T, He X, Zhang Z, Xie F, Wang S, Zhang L, Zhou F. The interaction between cGAS-STING pathway and pathogens. Signal Transduction and Targeted Therapy. 2020
·      Liu L, Wu Y, Zhang C, Zhou C, Li Y, Zeng Y, Zhang C, Li R, Luo D, Wang L, Zhang L, Tu S, Deng H, Luo S, Chen YG, Xiong X, Yan X. Cancer-associated adipocytes-derived G-CSF promotes breast cancer malignancy via Stat3 signaling.  J Mol Cell Biol. 2020
·      Zhou X, Xie F, Wang L, Zhang L, Zhang S, Fang M, Zhou F. The function and clinical application of extracellular vesicles in innate immune regulation. Cellular & Molecular Immunology. 2020